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A suggested positive control is SK-N-SH cell lysate.
PA5-21096 can be used with blocking peptide PEP-1210.
The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Each LRRTM protein is a type I transmembrane containing ten extracellular leucine-rich repeats and a short intracellular tail and has a developmentally regulated pattern distinct from all others. LRRTM1 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: leucine-rich repeat transmembrane neuronal 1; leucine-rich repeat transmembrane neuronal 1 protein; Leucine-rich repeat transmembrane neuronal protein 1
基因别名: 4632401D06Rik; AW125451; LRRTM1; UNQ675/PRO1309
UniProt ID: (Rat) D4A6D8, (Human) Q86UE6, (Mouse) Q8K377
Entrez Gene ID: (Rat) 679668, (Human) 347730, (Mouse) 74342
分子生物学功能: transmembrane signal receptor