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产品信息
PA5-52274
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.74 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2643656
产品详细信息
Immunogen sequence: TEVNAKASEI LGLKAQLKDT RGKLEGLELR TQDLEGALRT KGLELEVCEN ELQRKKNEAE LLREKVNLLE QELQELRAQA ALARDMGPPT FPEDVPALQR ELERLRAELR EERQGHDQMS SGFQHERLVW KE
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 86%.
靶标信息
This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: F37/Esophageal cancer-related gene-coding leucine-zipper motif; Fez1; Leucine zipper putative tumor suppressor 1; leucine zipper, putative tumor suppressor 1
基因别名: F37; FEZ1; LZTS1
UniProt ID: (Human) Q9Y250
Entrez Gene ID: (Human) 11178
