NeoBiotechnologies

Lambda Light Chain (B-Cell Marker) Recombinant Rabbit Monoclonal Antibody (IGL/9397R)

Lambda Light Chain (B-Cell Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Lambda Light Chain (B-Cell Marker) Antibody (3535-RBM19-P1ABX) in IHC (P)

Formalin-fixed, paraffin-embedded human tonsil stained with Lambda LC Recombinant Rabbit Monoclonal Antibody (IGL/9397R). Inset: PBS instead of primary antibody; secondary only negative control.

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产品信息

3535-RBM19-P1ABX

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG, kappa

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

IGL/9397R

抗原

Recombinant fragment (around aa1-200) of human IGL protein.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A/G

保存液

PBS

内含物

no preservative

保存条件

-20°C or -80°C if preferred

运输条件

Ambient (domestic); Dry ice (international)

产品详细信息

Positive Control: 293T Raji or hPBL cells. Human tonsil or spleen (IHC).

Cellular Location: Cell Surface. Cytoplasm. Secreted.

靶标信息

Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five types) and two light chains (kappa, lambda; both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30. Antibodies to the kappa light chain are reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

仅用于科研。不用于诊断过程。未经明确授权不得转售。