Invitrogen

Lambda light chain Monoclonal Antibody (A8G3)

Lambda light chain Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Lambda light chain Antibody (MA5-44936) in IHC (P)

Immunohistochemistry analysis of Lambda Light Chain in paraffin-embedded human tonsil tissue. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with Lambda Light Chain Monoclonal antibody (Product # MA5-44936) using a dilution of 1:4... View More

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产品信息

MA5-44936

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

免疫组化（石蜡） (IHC (P))

1:4,000

免疫细胞化学 (ICC/IF)

1:200

流式细胞分析 (Flow)

1 µg/mL

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2b

分类

Monoclonal

类型

Antibody

克隆号

A8G3

抗原

Constant region of natural protein (constant region of light chain lambda chain).

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

2 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4, with 40% glycerol, 0.1% BSA

内含物

0.05% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2931392

靶标信息

Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five types) and two light chains (kappa, lambda; both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30. Antibodies to the kappa light chain are reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

仅用于科研。不用于诊断过程。未经明确授权不得转售。