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IL1R2 Antibody (MA5-23626) in Flow
Flow cytometry of IL1R2 in Human peripheral blood mononuclear cells (PBMCs), stimulated to induce Regulatory T Cells (Tregs) and gated on CD4+, were treated with 10 µg/mL Anti-CD3, 5 µg/mL Anti-CD28, 10 ng/mL Recombinant Human TGF‚β1 , and 20 ng/mL Recombinant Human IL‚2 for 48 hours and stained with Rat Anti-Human LRRC32/GARP PE‚conjugated Monoclonal Antibody. Samples were incubated in either (A) IL1R2 monoclonal antibody (Product # MA5-23626) or (B) Mouse IgG1 Allophycocyanin Isotype Control.
产品信息
MA5-23626
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
34141
抗原
Sf 21-derived recombinant human IL-1 RII Phe14-Glu343 (Ser56Gly and Glu297Gly)
偶联物
激发/发射光谱
651/660 nm
查看光谱
形式
Liquid
纯化类型
Protein A/G
保存液
Buffered saline solution with 0.5% BSA
内含物
0.09% sodium azide
保存条件
4° C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2609076
产品详细信息
When used in combination with the biotinylated human IL-1 RII affinity purified polyclonal detection antibody in sandwich ELISAs, no significant cross-reactivity or interference was observed with recombinant human (rh) IL-1ra, rhIL-1 RI, recombinant mouse IL-1ra, or recombinant rat IL-1ra.
靶标信息
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
How to use the Panel Builder
Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.
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生物信息学
蛋白别名: antigen CDw121b; CD121 antigen-like family member B; CD121b; CDw121b; IL-1 type II receptor; IL-1R-2; IL-1R-beta; ILR2; interleukin 1 receptor type II variant 3; interleukin 1 receptor, type II; Interleukin-1 receptor beta; Interleukin-1 receptor type 2; Interleukin-1 receptor type II; type II interleukin-1 receptor, beta
基因别名: CD121b; CDw121b; IL-1R-2; IL-1RT-2; IL-1RT2; IL1R2; IL1R2c; IL1RB
UniProt ID: (Human) P27930
Entrez Gene ID: (Human) 7850
