Invitrogen

Phospho-HCLS1 (Tyr397) Recombinant Rabbit Monoclonal Antibody (HS1Y397-F12), PE

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Phospho-HCLS1 (Tyr397) Antibody in Flow Cytometry (Flow)

Phospho-HCLS1 (Tyr397) Antibody in Flow Cytometry (Flow)

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Phospho-HCLS1 (Tyr397) Antibody (MA5-37160) in Flow

Flow cytometry of Phospho-HS1 (Tyr397) using Ramos cells. Samples were incubated in monoclonal Phospho-HS1 (Tyr397) antibody (Product # MA5-37160). Images correspond with the following conditions: untreated, unstained negative control (blue), untreated (red), treated with pervanadate (green).

Phospho-HCLS1 (Tyr397) Antibody in Flow Cytometry (Flow)

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Phospho-HCLS1 (Tyr397) Antibody in Flow Cytometry (Flow) — Flow cytometry of Phospho-HS1 (Tyr397) using Ramos cells. Samples were incubated in monoclonal Phospho-HS1 (Tyr397) antibody (Product # MA5-37160). Images correspond with the following conditions: untreated, unstained negative control (blue), untreated (red), treated with pervanadate (green).

产品信息

MA5-37160

应用

建议稀释比

已发表文章

流式细胞分析 (Flow)

5 µL/1x10^6 cells

-

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG, kappa

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

HS1Y397-F12

抗原

A synthetic phospho-peptide corresponding to residues surrounding Tyr397 of human phospho HS1.

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偶联物

PE PE PE

激发/发射光谱

565/576 nm 查看光谱

形式

Liquid

纯化类型

Protein A/G

保存液

PBS with 0.20% BSA

内含物

0.09% sodium azide

保存条件

4° C

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2897094

靶标信息

Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression. [UniProt]

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Hematopoietic cell-specific LYN substrate 1; Hematopoietic lineage cell-specific protein; LckBP1; p75

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基因别名: AW213261; CTTNL; HCLS1; HS1; lckBP1; p75

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UniProt ID: (Human) P14317, (Mouse) P49710

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Entrez Gene ID: (Human) 3059, (Mouse) 15163

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RNA polymerase II transcription factor binding actin binding protein binding SH3 domain binding protein kinase binding protein complex binding actin or actin-binding cytoskeletal protein cytoskeletal protein non-motor actin binding protein

参与通路

negative regulation of transcription from RNA polymerase II promoter regulation of transcription, DNA-templated positive regulation of cell proliferation response to hormone positive regulation of phosphatidylinositol 3-kinase signaling actin filament polymerization erythrocyte differentiation regulation of actin filament polymerization positive regulation of granulocyte differentiation positive regulation of peptidyl-serine phosphorylation intracellular signal transduction positive regulation of tyrosine phosphorylation of STAT protein positive regulation of transcription factor import into nucleus positive regulation of macrophage differentiation positive regulation of transcription from RNA polymerase II promoter positive regulation of peptidyl-tyrosine phosphorylation positive regulation of protein kinase B signaling cellular response to cytokine stimulus negative regulation of leukocyte apoptotic process positive regulation of actin cytoskeleton reorganization