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Sequence of this protein is as follows: MARVPLGRSL TLSPRLEHNG MTSAHHNFRL PGSRDSPASA SQVAEIIDLE WYEKSEETHA SQIELLETSS TQEPLNASEA FCPRDCMVPV VFPGPVSQEG CCQFTCELLK HIMYQRQQLP LPYEQLKHFY RKPSPQAEEM LKKKPRATTE VSSRKCQQAL AELESVLSHL EDFFARTLVP RVLILLGGNA LSPKEFYELD LSLLAPYSVD QSLSTAACLR RLFRAIFMAD AFSELQAPPL MGTVVMAQGH RNCGEDWFRP KLNYRVPSRG HKLTVTLSCG RPSIRTTAWE DYIWFQAPVT FKGFRE
The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Caught by MAD2 protein; MAD2L1-binding protein; p31(comet); RP1-261G23.6
基因别名: 0610009D16Rik; 2510031P20Rik; AU018945; AW550977; C76045; CMT2; CMT2A; CMT2B; KIAA0110; MAD2L1BP; Mad2lbp; mKIAA0110
UniProt ID: (Human) Q15013, (Mouse) Q9DCX1
Entrez Gene ID: (Human) 9587, (Mouse) 66591