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产品信息
PA5-20784
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 14 amino acid peptide near the center of human MAK10.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11154505
产品详细信息
A suggested positive control is mouse heart tissue lysate.
PA5-20784 can be used with blocking peptide PEP-0898.
靶标信息
The MAK10 gene encodes a 733-amino acid protein with several regions of similarity to T cell receptor alpha-subunit V (variable) regions in yeast. The mammalian homologue of yeast MAK10, also known as EGAP, is one subunit of a novel N-terminal acetyltransferase (NAT) that is highly conserved among vertebrate species. It is expressed in a variety of tissues in the developing rat embryo but restricted in expression in the adult, remaining detectable only in tissues undergoing continual cell renewal or in cells responding to pathological injury. The MAK10-NAT complex is an essential regulatory enzyme controlling the function of a subset of proteins required for embryonic growth control and vessel development. This complex functionally co-assembles in mammalian cells to regulate cell proliferation and is essential for embryonic development, at least in part through the regulation of target of rapamycin (TOR) signaling events. At least two isoforms of MAK10 are known to exist.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: corneal wound healing related protein; corneal wound healing-related protein; Corneal wound-healing-related protein; Embryonic growth-associated protein; Embryonic growth-associated protein homolog; MAK10 homolog, amino-acid N-acetyltransferase subunit; N-alpha-acetyltransferase 35, NatC auxiliary subunit; Nalpha acetyltransferase 35; Protein MAK10 homolog; RAT52; RP11-379P1.1
基因别名: A330021G12Rik; A330027C19Rik; AI158944; bA379P1.1; C030004C14Rik; EGAP; Emb8; MAK10; MAK10P; NAA35; T4a
UniProt ID: (Human) Q5VZE5, (Mouse) Q6PHQ8, (Rat) Q6DKG0
Entrez Gene ID: (Human) 60560, (Mouse) 78689, (Rat) 64472
