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产品信息
PA5-72734
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
LEMD3 antibody for an 18 amino acid synthetic peptide near the carboxy terminus of human LEMD3. The immunogen is within the last 50 amino acids of LEMD3.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2718588
靶标信息
Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced cell proliferation arrest.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Inner nuclear membrane protein Man1; integral inner nuclear membrane protein; integral inner nuclear membrane protein MAN1; LEM domain-containing protein 3
基因别名: AI316861; LEMD3; MAN1
UniProt ID: (Human) Q9Y2U8, (Mouse) Q9WU40
Entrez Gene ID: (Human) 23592, (Mouse) 380664
negative regulation of transforming growth factor beta receptor signaling pathway
negative regulation of BMP signaling pathway
negative regulation of activin receptor signaling pathway
angiogenesis
blood vessel endothelial cell migration involved in intussusceptive angiogenesis
nucleus organization
skeletal muscle cell differentiation
regulation of cell cycle
regulation of extracellular matrix organization
