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Immunogen sequence: MENQEKASIA GHMFDVVVIG GGISGLSAAK LLTEYGVSVL VLEARDRVGG RTYTIRNEHV DYVDVGGAYV GPTQNRILRL SKELGIETYK VNVSERLVQY VKGKTYPFRG AFPPVWNPIA YLDYNNLWRT IDNMGKEIPT DAPWEAQHAD KWDKMTMKEL IDKICWTKTA RRFAYLFVNI NVTSEPHEVS ALWFLWYVKQ CGGTTRIFSV TNGGQERKFV GGSGQVSERI MDLLGDQVKL NHPVTHVDQS SDNIIIETLN; Positive Samples: A-549, PC-3, HeLa, HT-29, Mouse lung, Mouse intestine, Mouse kidney, Mouse liver, NCI-H460; Cellular Location: Cytoplasmic side, Mitochondrion outer membrane, Single-pass type IV membrane protein
This gene encodes monoamine oxidase A, an enzyme that degrades amine neurotransmitters, such as dopamine, norepinephrine, and serotonin. The protein localizes to the mitochondrial outer membrane. The gene is adjacent to a related gene on the opposite strand of chromosome X. Mutation in this gene results in monoamine oxidase deficiency, or Brunner syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Amine oxidase [flavin-containing] A; HGNC:6833; MAO-A; Monoamine oxidase type A; RP1-201D17__B.2
基因别名: 1110061B18Rik; AA407771; Mao; MAO-A; MAOA
UniProt ID: (Human) P21397, (Mouse) Q64133
Entrez Gene ID: (Human) 4128, (Mouse) 17161, (Rat) 29253