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MA5-17118 targets MARK3 in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with Human and Mouse samples.
The MA5-17118 immunogen is purified recombinant fragment of human MARK3 (amino acids: 435-658) expressed in E. Coli.
MA5-17118 detects MARK3 which has a predicted molecular weight of approximately 87kDa.
MARK3 is a member of a group of kinases known to regulate cell polarity via phosphorylation of microtubule-associated proteins (MAPs). The protein encoded by MARK3 is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4. Several transcript variants encoding different isoforms have been found for MARK3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C-TAK1; Cdc25C-associated protein kinase 1; cTAK1; ELKL motif kinase 2; EMK-2; EMK2/MARK3 serine-threonine protein kinase; MAP/microtubule affinity-regulating kinase 3; MPK-10; Par-1a; Protein kinase STK10; Ser/Thr protein kinase PAR-1; Serine/threonine-protein kinase p78
基因别名: 1600015G02Rik; A430080F22Rik; C-TAK1; CTAK1; EMK2; ETK-1; ETK1; KP78; MARK3; MPK10; Par-1a; PAR1A
UniProt ID: (Human) P27448, (Mouse) Q03141
Entrez Gene ID: (Human) 4140, (Mouse) 17169