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产品信息
PA5-75277
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 221-270 of Human MBD3.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2719005
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
Regulator of genomic integrity and cellular response to DNA damage acting through ATR-mediated checkpoint signaling. Necessary for centrosome duplication. It functions as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, two molecules involved in centriole formation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CpG binding domain 3; Methyl-CpG-binding domain protein 3; Methyl-CpG-binding protein MBD3
基因别名: AI181826; AU019209; MBD3
UniProt ID: (Human) O95983, (Mouse) Q9Z2D8
Entrez Gene ID: (Human) 53615, (Mouse) 17192, (Rat) 362834
negative regulation of transcription from RNA polymerase II promoter
in utero embryonic development
methylation-dependent chromatin silencing
transcription, DNA-templated
brain development
heart development
aging
tissue development
histone acetylation
histone deacetylation
response to nutrient levels
response to estradiol
ATP-dependent chromatin remodeling
regulation of DNA methylation
embryonic organ development
regulation of signal transduction by p53 class mediator
response to organic cyclic compound
