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产品信息
PA5-33924
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 18 amino acid peptide from C-Terminus of human MC3 Receptor.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2551292
产品详细信息
Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Gibbon, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Horse, Pig (94%); Bat, Rabbit, Platypus (89%); Opossum, Turkey, Chicken, Xenopus, Trout (83%).
Immunohistochemistry with formalin-fixed paraffin-embedded tissues requires pretreatment with Proteinase K.
靶标信息
This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MC3 receptor; MC3-R; Melanocortin receptor 3; obesity quantitative trait locus
基因别名: BMIQ9; MC3; MC3-R; MC3R; OB20; OQTL
UniProt ID: (Human) P41968
Entrez Gene ID: (Human) 4159
regulation of heart rate
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
regulation of blood pressure
positive regulation of cAMP biosynthetic process
circadian regulation of gene expression
homoiothermy
locomotor rhythm
sodium ion homeostasis
regulation of feeding behavior
