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MCT1 (SLC16A1) (extracellular) Antibody (AMT-011-APC50UL) in Flow
Cell surface detection of monocarboxylate transporter 1 by direct flow cytometry in live intact human Jurkat T-cell leukemia cells: - (black line) cells. (red) Cells + Rabbit IgG Isotype control-APC (#RIC-001-APC). (green) Cells + Anti-MCT1 (SLC16A1) (extracellular)-APC Antibody (#AMT-011-APC), (5 µg).
产品信息
AMT-011-APC50UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)GRLNDMYGDYKYT, corresponding to amino acid residues 403-415 of rat MCT1, Extracellular, 6th loop
偶联物
激发/发射光谱
651/660 nm
查看光谱
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 50 µL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
SLC16A1 is a monocarboxylate transporter (MCT1) that mediates the movement of lactate and pyruvate across cell membranes. Import and export of these substrates by tissues such as erythrocytes, muscle, intestine, and kidney are ascribed largely to the action of a proton-coupled MCT.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ36745; MCT 1; MGC44475; monocarboxylate transporter; Monocarboxylate transporter 1; SLC16A1 protein; solute carrier 16 (monocarboxylic acid transporter), member 1; solute carrier family 16 (monocarboxylate transporter), member 1; solute carrier family 16 (monocarboxylic acid transporters), member 1; Solute carrier family 16 member 1; solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
基因别名: AL022710; HHF7; MCT; MCT1; MCT1D; RATMCT1; RNMCT1; SLC16A1
UniProt ID: (Human) P53985, (Rat) P53987, (Mouse) P53986
Entrez Gene ID: (Human) 6566, (Rat) 25027, (Mouse) 20501
monocarboxylic acid transmembrane transporter activity
lactate transmembrane transporter activity
mevalonate transmembrane transporter activity
symporter activity
protein homodimerization activity
organic cyclic compound binding
protein binding
secondary active monocarboxylate transmembrane transporter activity
transporter
pyruvate metabolic process
lipid metabolic process
monocarboxylic acid transport
mevalonate transport
response to food
plasma membrane lactate transport
glucose homeostasis
regulation of insulin secretion
leukocyte migration
centrosome organization
behavioral response to nutrient
cellular response to organic cyclic compound
lactate transmembrane transport
transport
transmembrane transport
