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Antibody detects endogenous levels of total ME3.
ME3 proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis, metastasis, and atherosclerosis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HME; malate dehydrogenase; malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); Malic enzyme 3; malic enzyme 3, NADP(+)-dependent, mitochondrial; malic enzyme, NADP+-dependent, mitochondrial; mitochondrial NADP(+)-dependent malic enzyme 3; MMP3; NADP-dependent malic enzyme, mitochondrial; NADP-ME; pyruvic-malic carboxylase
基因别名: 1700020C08Rik; B230207H15Rik; ME3; NADP-ME
UniProt ID: (Human) Q16798, (Mouse) Q8BMF3
Entrez Gene ID: (Human) 10873, (Mouse) 109264
分子生物学功能:
oxidoreductase