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Alomone Labs, LTD
MEGF10 (extracellular) Polyclonal Antibody
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MEGF10 (extracellular) Antibody (ANR-205-200UL) in IHC (F)
Expression of MEGF10 in rat substantia nigra. Immunohistochemical staining of perfusion-fixed frozen rat brain sections with Anti-MEGF10 (extracellular) Antibody (#ANR-205) (1:300), followed by goat anti-rabbit-AlexaFluor-488. A. MEGF10 immunoreactivity (green) appears in neurons (arrows). B. Pre-incubation of the antibody with MEGF10 (extracellular) Blocking Peptide (BLP-NR205), suppressed staining. Cell n... View More
产品信息
ANR-205-200UL
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide CDAGEQAVRKGAR, corresponding to amino acid residues 95-108 of mouse CARTPT. Secreted.
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunogen sequence: CDAGEQAVRKGAR
Reconstitution: 25 uL, 50 uL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. Expression of this gene may be associated with schizophrenia, and mutations in this gene are a cause of early-onset myopathy, areflexia, respiratory distress, and dysphagia (EMARDD) as well as congenital myopathy with minicores. Alternatively spliced transcript variants have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Multiple EGF-like domains protein 10; multiple EGF-like-domains 10; Multiple epidermal growth factor-like domains protein 10
基因别名: 3000002B06Rik; EMARDD; Gm331; KIAA1780; MEGF10
UniProt ID: (Human) Q96KG7, (Mouse) Q6DIB5
Entrez Gene ID: (Human) 84466, (Mouse) 70417, (Rat) 291445
skeletal muscle satellite cell activation
skeletal muscle satellite cell differentiation
skeletal muscle satellite cell proliferation
homotypic cell-cell adhesion
recognition of apoptotic cell
regulation of skeletal muscle tissue development
regulation of muscle cell differentiation
muscle cell development
phagocytosis
cell adhesion
muscle organ development
myelination
