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产品信息
PA5-109954
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 300-390 of human MEIS1 (NP_0023891)
偶联物
形式
Liquid
浓度
0.72 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2855365
产品详细信息
Immunogen sequence: PSEEQKKQLA QDTGLTILQV NNWFINARRR IVQPMIDQSN RAVSQGTPYN PDGQPMGGFV MDGQQHMGIR APGPMSGMGM NMGMEGQWHY M
靶标信息
Homeobox genes, of which the most well-characterized category is represented by the HOX genes, play a crucial role in normal development. In addition, several homeoproteins are involved in neoplasia. This gene encodes a homeobox protein belonging to the TALE family of homeodomain-containing proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Homeobox protein Meis1; leukemogenic homolog protein; Meis1, myeloid ecotropic viral integration site 1 homolog; MGC43380; Myeloid ecotropic viral integration site 1; WUGSC:H_NH0444B04.1
基因别名: C530044H18Rik; Evi8; MEIS1
UniProt ID: (Human) O00470, (Mouse) Q60954
Entrez Gene ID: (Human) 4211, (Rat) 686117, (Mouse) 17268
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
protein heterodimerization activity
DNA binding
sequence-specific DNA binding
homeodomain transcription factor
angiogenesis
lens morphogenesis in camera-type eye
transcription from RNA polymerase II promoter
locomotory behavior
megakaryocyte development
negative regulation of myeloid cell differentiation
negative regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
definitive hemopoiesis
regulation of transcription, DNA-templated
hemopoiesis
blood vessel morphogenesis
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
multicellular organism development
