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Immunogen sequence: LDICSKNPCH NGGLCEEISQ EVRGDVFPSY TCTCLKGYAG NHCETKCVEP LGLENGNIAN SQIAASSVRV TFLGLQHWVP ELARLNRAGM VNAWTPSSND DNPWIQVNLL RRMWVTGVVT QGASRLASHE YLKAFKVAYS LNGHEFDFIH DVNKKHKEFV GNWNKNAVHV NLFETPVEAQ YVRLYPTSCH TACTLRFELL
This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AGS; Breast epithelial antigen BA46; EGF/factor VIII; HMFG; Lactadherin; medin; MFG-E8; MFGM; milk fat globule glycoprotein; milk fat globule membrane; milk fat globule membrane protein; Milk fat globule-EGF factor 8; MP47; O-acetyl disialoganglioside synthase; O-acetyl GD3 ganglioside synthase; O-acetyltransferase milk fat globule membrane protein; O-acetyltransferase Milk fat glolbule membrane protein; SED1; sperm associated antigen 10; sperm surface protein hP47; Sperm surface protein SP47
基因别名: AA408458; AGS; AI325141; BA46; EDIL1; HMFG; hP47; HsT19888; lactadherin; MFG-E8; MFGE8; MFGM; MFGME8; MFGMP-E8; MP47; OAcGD3S; P47; SED1; SPAG10
UniProt ID: (Human) Q08431, (Mouse) P21956, (Rat) P70490
Entrez Gene ID: (Human) 4240, (Mouse) 17304, (Rat) 25277