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MFI2 Antibody (PA5-32921) in IHC (P)
Immunohistochemistry analysis of MFI2 in human brain, cortex. Samples were incubated with MFI2 polyclonal antibody (Product # PA5-32921). Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
产品信息
PA5-32921
产品规格
种属反应
Bat,
Horse,
Hamster,
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 15 amino acid peptide from N-terminus of human MFI2.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2550382
产品详细信息
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bat, Hamster, Elephant, Panda, Horse (100%); Bovine, Rabbit, Pig (93%); Chicken, Platypus (87%); Dog, Turkey, Medaka, Zebrafish (80%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
靶标信息
The protein encoded by this gene is a cell-surface glycoprotein found on melanoma cells. The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily. The importance of the iron binding function has not yet been identified. This gene resides in the same region of chromosome 3 as members of the transferrin superfamily. Alternative splicing results in two transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5; CD228; Melanoma-associated antigen p97; melanoma-associated antigen p97, isoform 2; Melanotransferrin; membrane-bound transferrin-like protein; Membrane-bound transferrin-like protein p97; MTf
基因别名: CD228; MAP97; MELTF; MFI2; MTf; MTF1
UniProt ID: (Human) P08582, (Mouse) Q9R0R1
Entrez Gene ID: (Horse) 100060123, (Human) 4241, (Mouse) 30060, (Chinese hamster) 100750333, (Rat) 288038
regulation of cell growth
positive regulation of plasminogen activation
regulation of cell proliferation
iron ion homeostasis
positive regulation of extracellular matrix disassembly
iron ion import
negative regulation of substrate adhesion-dependent cell spreading
transport
ion transport
cellular iron ion homeostasis
