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产品信息
PA5-21050
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 15 amino acid peptide near the center of human MFSD2B.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11155222
产品详细信息
A suggested positive control is rat lung tissue lysate.
PA5-21050 can be used with blocking peptide PEP-1164.
靶标信息
Multidrug transporters, such as MFSD2B, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. Major Facilitator Superfamily (MFS) members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFSD2B is closely related to MFSD2A, which is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting, playing a major role in the induction of MFSD2A expression during adaptive thermogenesis. Unlike MFSD2A, MFSD2B is expressed in few tissues and at relatively low levels, and is not induced during fasting, suggesting that MFSD2B may play other roles.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hMfsd2b; major facilitator superfamily domain containing 2B; Major facilitator superfamily domain-containing protein 2B; Sphingosine-1-phosphate transporter MFSD2B
基因别名: MFSD2B; RGD1561716
UniProt ID: (Human) A6NFX1
Entrez Gene ID: (Human) 388931, (Rat) 500624
