Invitrogen

MGARP Polyclonal Antibody

高级验证

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

查看其他3个MGARP抗体

说明书

实验方案

技术支持

说明书

实验方案

技术支持

抗体检测数据 (7)
高级验证 (1)

MGARP Antibody in Immunocytochemistry (ICC/IF)

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MGARP Antibody (PA5-64966) in ICC/IF

Immunofluorescent staining of MGARP in human cell line BJ shows localization to mitochondria. Samples were probed using a MGARP Polyclonal Antibody (Product # PA5-64966).

MGARP Antibody in Immunohistochemistry (Paraffin) (IHC (P))

MGARP Antibody in Immunohistochemistry (IHC)

Product Image Gallery

MGARP Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of MGARP demonstrates antibody specificity. Immunohistochemical analysis of MGARP using anti-MGARP Polyclonal Antibody (Product # PA5-64966), shows significant staining of MGARP in human adrenal gland and shows minimal or weak staining in human cerebral cortex tissues. The relative expression levels of MGARP within each tissue is shown using RNA-Seq. {RE}

产品信息

PA5-64966

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:2,500-1:5,000

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant Human MGARP. Recombinant protein control fragment (Product #RP-105737).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.25 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2664184

产品详细信息

Immunogen sequence: YKTVTSDQAKH TEHKTNLKEK TKAEIHPFQG EKENVAETEK ASSEAPEELI VEAEVVDAEE SPSATVVVIK EASACPGHVE AAPETTAVSA ETGPEVTDAA A

Highest antigen sequence identity to the following orthologs - mouse 44%, rat 45%.

靶标信息

MGARP plays a role in the trafficking of mitochondria along microtubules. It regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia. It participates in the translocation of TRAK2/GRIF1 from the cytoplasm to the mitochondrion. It also plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: CESP-1; Corneal endothelium-specific protein 1; Hypoxia up-regulated mitochondrial movement regulator protein; Mitochondria-localized glutamic acid-rich protein; Ovary-specific acidic protein; Protein MGARP

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基因别名: C4orf49; CESP-1; CESP1; GS3582; HUMMR; MGARP; OSAP

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UniProt ID: (Human) Q8TDB4

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Entrez Gene ID: (Human) 84709

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功能

protein binding

参与通路

protein targeting to mitochondrion anterograde axonal transport retrograde axonal transport regulation of mitochondrion organization positive regulation of mitochondrion organization axonal transport of mitochondrion cellular response to steroid hormone stimulus cellular response to hypoxia cellular response to gonadotropin-releasing hormone