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MGARP Antibody (MA5-27537) in IHC (P)
Immunohistochemistry was performed on paraffin-embedded human testicle tissue. To expose target proteins, heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min. Following antigen retrieval, tissues were probed with a MGARP monoclonal antibody (Product # MA5-27537) at a dilution of 1:500.
产品信息
MA5-27537
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI5B6
抗原
Full length human recombinant protein of MGARP produced in E.coli
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2724684
靶标信息
MGARP plays a role in the trafficking of mitochondria along microtubules. It regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia. It participates in the translocation of TRAK2/GRIF1 from the cytoplasm to the mitochondrion. It also plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CESP-1; Corneal endothelium-specific protein 1; Hypoxia up-regulated mitochondrial movement regulator protein; Mitochondria-localized glutamic acid-rich protein; Ovary-specific acidic protein; Protein MGARP
基因别名: C4orf49; CESP-1; CESP1; GS3582; HUMMR; MGARP; OSAP
UniProt ID: (Human) Q8TDB4
Entrez Gene ID: (Human) 84709
protein targeting to mitochondrion
anterograde axonal transport
retrograde axonal transport
regulation of mitochondrion organization
positive regulation of mitochondrion organization
axonal transport of mitochondrion
cellular response to steroid hormone stimulus
cellular response to hypoxia
cellular response to gonadotropin-releasing hormone
