Search Thermo Fisher Scientific
This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 79%
Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAcbeta1,2-Manalpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAcbeta1,2-Manalpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B; mannoside acetylglucosaminyltransferase 5, isoenzyme B; N-acetylglucosaminyltranferase VB
Entrez Gene ID: (Rat) 303693
分子生物学功能: glycosyltransferase