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产品信息
MA5-28816
产品规格
种属反应
Avian,
Chicken
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
F21-2
偶联物
激发/发射光谱
498/517 nm
查看光谱
形式
Liquid
浓度
0.5 mg/mL
纯化类型
purified
保存液
PBS, pH 7.4
内含物
<0.1% sodium azide
保存条件
4° C, store in dark
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2745775
靶标信息
Like their mammalian counterparts, avian MHC Class I molecules, also known as B-F antigens, consist of a highly polymorphic alpha-chain noncovalently bound to the invariant beta2-microglobulin subunit. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. The monoclonal antibody F21-2 also reacts with turkey MHC Class I.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
How to use the Panel Builder
Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.
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生物信息学
蛋白别名: alpha chain 2; antigen presentation; antigen presentation; BFIV major; BF12 major; B-F antigen; G-B1; B-F histocompatibility F10 antigen; B-F major; B-F minor; B-F-beta-IV; chicken MHC class I antigen; class I histocompatibility antigen, F10 alpha chain; F10 alpha chain; major histocompatibility complex class I glycoprotein; major histocompatibility complex, class I, G; MHC BF2 class I; MHC class I alpha chain 1; MHC class I alpha chain 2; MHC class I antigen alpha chain; MHC class I antigen B-F heavy chain; MHC class I antigen B-F major heavy chain; MHC class I antigen B-F minor heavy chain; MHC class I antigen heavy chain; MHC class I glycoprotein; MHC class I molecule; MHC class1 antigen; minor antigen
基因别名: B-F; B-F-S01; B-F-S02; B-F-S03; B-F-S04; B-F-S05; B-F-S06; B-F-S07; B-F-S09; B-F-S11; B-F-S12; B-F-S13; B-F-S14; B-F1; B-FI; B-FIV; B-LB2; B12; BF; BF12; BF2; BFa1; BFa2; BFIV; BFIV21; BFw-03; BFw-05; BFz-01; HFE
Entrez Gene ID: (Chicken) 693260, (Chicken) 425389
