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产品信息
MA5-28818
产品规格
种属反应
Avian,
Chicken
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
F21-2
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
purified
保存液
BBS, pH 8.2
内含物
no preservative
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2745777
靶标信息
Like their mammalian counterparts, avian MHC Class I molecules, also known as B-F antigens, consist of a highly polymorphic alpha-chain noncovalently bound to the invariant beta2-microglobulin subunit. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. The monoclonal antibody F21-2 also reacts with turkey MHC Class I.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
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生物信息学
蛋白别名: alpha chain 2; antigen presentation; antigen presentation; BFIV major; BF12 major; B-F antigen; G-B1; B-F histocompatibility F10 antigen; B-F major; B-F minor; B-F-beta-IV; chicken MHC class I antigen; class I histocompatibility antigen, F10 alpha chain; F10 alpha chain; major histocompatibility complex class I glycoprotein; major histocompatibility complex, class I, G; MHC BF2 class I; MHC class I alpha chain 1; MHC class I alpha chain 2; MHC class I antigen alpha chain; MHC class I antigen B-F heavy chain; MHC class I antigen B-F major heavy chain; MHC class I antigen B-F minor heavy chain; MHC class I antigen heavy chain; MHC class I glycoprotein; MHC class I molecule; MHC class1 antigen; minor antigen
基因别名: B-F; B-F-S01; B-F-S02; B-F-S03; B-F-S04; B-F-S05; B-F-S06; B-F-S07; B-F-S09; B-F-S11; B-F-S12; B-F-S13; B-F-S14; B-F1; B-FI; B-FIV; B-LB2; B12; BF; BF12; BF2; BFa1; BFa2; BFIV; BFIV21; BFw-03; BFw-05; BFz-01; HFE
Entrez Gene ID: (Chicken) 693260, (Chicken) 425389
