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MIER1 Antibody (PA5-54032) in ICC/IF
Immunofluorecent analysis of MIER1 in human cell line A-431 using MIER1 Polyclonal Antibody (Product # PA5-54032). Staining shows localization to nucleoplasm.
产品信息
PA5-54032
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2643969
产品详细信息
Immunogen sequence: MMEGETNFSS EIEDLAREGD MPIHELLSLY GYGSTVRLPE EDEEEEEEEE EGEDDEDADN DDNSGCSGEN KEENIKDSSG QEDETQSSND DPSQSVASQD AQEI
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 96%.
靶标信息
The association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function in the regulation of transcription. Repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Early response 1; hMI-ER1; mesoderm induction early response 1 homolog; mesoderm induction early response 1, transcriptional regulator; Mesoderm induction early response protein 1; RP5-944N15.1
基因别名: ER1; KIAA1610; MI-ER1; MIER1
UniProt ID: (Human) Q8N108
Entrez Gene ID: (Human) 57708
