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The antibody detects endogenous levels of total MRPL15 protein.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 39S ribosomal protein L15, mitochondrial; L15mt; Large ribosomal subunit protein uL15m; MRP-L15; ribosomal protein, mitochondrial, L7
基因别名: HSPC145; L15mt; MRP-L15; MRP-L7; MRPL15; RPML7
UniProt ID: (Human) Q9P015, (Mouse) Q9CPR5
Entrez Gene ID: (Human) 29088, (Mouse) 27395
分子生物学功能:
ribosomal protein