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Positive test controls include: DU145, K-562, A-431, 293T, Mouse liver, Mouse heart, Mouse kidney, Rat liver. The target is usually found in the following locations: Mitochondrion.
Immunogen sequence: ELTEMRNDLF NKEKARQLSL TPRTEKIEVK HVGKTDPGTV FVMNKNISTP YSCAMHLSEW YCRKSILALV DGQPWDMYKP LTKSCEIKFL TFKDCDPGEV NKAYWRSCAM MMGCVIERAF KDEYMVNLVR APEVPVISGA FCYDVVLDSK LDEWMPTKEN LRSFTKDAHA LIYKDLPFET LEVEAKVALE IFQHSKYKVD FIEEKASQNP ERIVKLHRIG DFIDVSEGPL IPRTSICFQY EVSAVHNLQP TQPSLIRRFQ GVSLPVHLRA HFTIWDKLLE RSRKMVTEDQ SKATEECTST
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 39S ribosomal protein L39, mitochondrial; 39S ribosomal protein L5, mitochondrial; L39mt; L5mt; Large ribosomal subunit protein mL39; mitochondrial ribosomal protein L39; MRP-L39; ribosomal protein, mitochondrial, L5
基因别名: C21orf8; C21orf92; L39mt; MRP-L5; MRPL39; MRPL5; MSTP003; ORF22; PRED22; PRED66; RPML5
UniProt ID: (Human) Q9NYK5, (Mouse) Q9JKF7
Entrez Gene ID: (Human) 54148, (Rat) 684304, (Mouse) 27393
分子生物学功能: aminoacyl-tRNA synthetase