Invitrogen

MSTN Polyclonal Antibody

查看其他17个Myostatin抗体

抗体检测数据 (6)

MSTN Antibody in Immunohistochemistry (Paraffin) (IHC (P))

MSTN Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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MSTN Antibody (PA5-115278) in IHC (P)

Immunohistochemistry analysis of MSTN in human liver cancer and adjacent normal tissues. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115278) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.

MSTN Antibody in Immunohistochemistry (Paraffin) (IHC (P))

MSTN Antibody in Immunohistochemistry (Paraffin) (IHC (P))

MSTN Antibody in Immunohistochemistry (Paraffin) (IHC (P))

MSTN Antibody in Immunohistochemistry (Paraffin) (IHC (P))

MSTN Antibody in Immunohistochemistry (Paraffin) (IHC (P))

MSTN Antibody in Western Blot (WB)

Product Image Gallery

MSTN Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry analysis of MSTN in human liver cancer and adjacent normal tissues. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115278) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.

MSTN Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry analysis of MSTN in human kidney cancer. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115278) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.

MSTN Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry analysis of MSTN in human liver cancer. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115278) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.

MSTN Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry analysis of MSTN in mouse heart tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115278) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.

MSTN Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry analysis of MSTN in rat heart tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115278) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.

MSTN Antibody in Western Blot (WB) — Western blot analysis of MSTN in mouse brain (left lane: treated with blocking peptide). Samples were incubated with polyclonal antibody (Product # PA5-115278).

产品信息

PA5-115278

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

-

免疫组化（石蜡） (IHC (P))

1:50-1:200

-

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human MSTN(Accession O14793), corresponding to amino acid residues T240-F290.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

RRID

AB_2899914

产品详细信息

Antibody detects endogenous levels of total GDF8 / Myostatin.

靶标信息

The protein encoded by this gene is a member of the bone morphogenetic protein family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: compact; GDF-8; growth differentiation factor 8; Growth/differentiation factor 8; H-Myo-Propeptide; H-Myostatin; Myostatin

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基因别名: Cmpt; GDF8; MSLHP; MSTN

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UniProt ID: (Human) O14793, (Rat) O35312, (Mouse) O08689

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Entrez Gene ID: (Human) 2660, (Rat) 29152, (Mouse) 17700

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receptor binding cytokine activity transforming growth factor beta receptor binding protein binding growth factor activity heparin binding identical protein binding molecular_function growth factor

参与通路

positive regulation of defense response to virus by host transforming growth factor beta receptor signaling pathway muscle organ development response to heat response to gravity positive regulation of pathway-restricted SMAD protein phosphorylation skeletal muscle atrophy negative regulation of muscle hypertrophy response to muscle activity ovulation cycle process response to testosterone negative regulation of kinase activity regulation of apoptotic process skeletal muscle tissue regeneration regulation of MAPK cascade response to estrogen response to ethanol negative regulation of myoblast differentiation positive regulation of transcription, DNA-templated negative regulation of insulin receptor signaling pathway muscle cell cellular homeostasis cell development negative regulation of skeletal muscle tissue growth response to electrical stimulus negative regulation of protein kinase B signaling SMAD protein signal transduction cellular response to dexamethasone stimulus mitophagy in response to mitochondrial depolarization xenophagy negative regulation of skeletal muscle satellite cell proliferation negative regulation of satellite cell differentiation negative regulation of myoblast proliferation response to glucocorticoid growth