Invitrogen

MSX1 Polyclonal Antibody

查看其他13个MSX1抗体

抗体检测数据 (2)

MSX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

MSX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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MSX1 Antibody (PA5-18284) in IHC (P)

Immunohistochemistry analysis of MSX1 in human prostate. Samples were incubated with MSX1 polyclonal antibody (Product # PA5-18284) using a dilution of 5 µg/mL. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

MSX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

MSX1 Antibody in Western Blot (WB)

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MSX1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry analysis of MSX1 in human prostate. Samples were incubated with MSX1 polyclonal antibody (Product # PA5-18284) using a dilution of 5 µg/mL. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

MSX1 Antibody in Western Blot (WB) — Western blot analysis of MSX1 using MSX1 Polyclonal Antibody (Product # PA5-18284) (0.3 µg/mL) in staining of Human Prostate lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

产品信息

PA5-18284

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1 µg/mL

-

免疫组化（石蜡） (IHC (P))

2-4 µg/mL

-

产品规格

种属反应

Human

宿主/亚型

Goat / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide sequence (TSLPLGVKVEDS) corresponding to the N-terminus amino acids of MSX1

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Ammonium sulfate precipitation

保存液

TBS, pH 7.3, with 0.5% BSA

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_10977913

产品详细信息

This antibody is predicted to react with bovine, mouse, porcine and rat based on sequence homology.

This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.

靶标信息

MSX1 is a member of the muscle segment homeobox gene family. It functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. MSX1 may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition. Mutations in the gene, which was once known as homeobox 7, have been associated with nonsyndromic cleft lip with or without cleft palate 5, Witkop syndrome, Wolf-Hirschom syndrome, and autosomoal dominant hypodontia.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: homeobox 7; Homeobox protein Hox-7; Homeobox protein MSX-1; msh homeo box 1; Msh homeobox 1-like protein; msh homeobox homolog 1

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基因别名: ECTD3; HOX7; HYD1; MSX1; STHAG1

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UniProt ID: (Human) P28360

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Entrez Gene ID: (Human) 4487

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RNA polymerase II regulatory region sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding p53 binding homeodomain transcription factor

参与通路

negative regulation of transcription from RNA polymerase II promoter cell morphogenesis in utero embryonic development epithelial to mesenchymal transition involved in endocardial cushion formation transcription from RNA polymerase II promoter muscle organ development negative regulation of cell proliferation anterior/posterior pattern specification mesenchymal cell proliferation signal transduction involved in regulation of gene expression negative regulation of cell growth positive regulation of BMP signaling pathway forebrain development midbrain development protein localization to nucleus embryonic forelimb morphogenesis embryonic hindlimb morphogenesis embryonic nail plate morphogenesis middle ear morphogenesis odontogenesis of dentin-containing tooth regulation of odontogenesis negative regulation of apoptotic process positive regulation of DNA damage response, signal transduction by p53 class mediator positive regulation of transcription from RNA polymerase II promoter stem cell differentiation protein stabilization negative regulation of striated muscle cell differentiation palate development face morphogenesis bone morphogenesis cartilage morphogenesis mammary gland epithelium development BMP signaling pathway involved in heart development activation of meiosis positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator negative regulation of transcription regulatory region DNA binding positive regulation of mesenchymal cell apoptotic process