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产品信息
PA5-40475
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the C-terminal of human MTF1 (aa 562-611).
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2607817
产品详细信息
Peptide sequence: QSSLVMGEQN LQWILNGATS SPQNQEQIQQ ASKVEKVFFT TAVPVASSPG
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%
靶标信息
This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Metal regulatory transcription factor 1; metal-regulatory transcription factor 1; metal-responsive transcription factor 1; MRE-binding transcription factor; MRE-binding transcription factor-1; Transcription factor MTF-1; zinc regulatory factor
基因别名: MTF-1; MTF1; ZRF
UniProt ID: (Human) Q14872
Entrez Gene ID: (Human) 4520
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
core promoter binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
histone acetyltransferase binding
metal ion binding
C2H2 zinc finger transcription factor
