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产品信息
H00010797-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
4G7-2G3
抗原
MTHFD2 (AAH01548, 16 a.a. approximately 344 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: SLRLRPFHLA AVRNEAVVIS GRKLAQQIKQ EVRQEVEEWV ASGNKRPHLS VILVGENPAS HSYVLNKTRA AAVVGINSET IMKPASISEE ELLNLINKLN NDDNVDGLLV QLPLPEHIDE RRICNAVSPD KDVDGFHVIN VGRMCLDQYS MLPATPWGVW EIIKRTGIPT LGKNVVVAGR SKNVGMPIAM LLHTDGAHER PGGDATVTIS HRYTPKEQLK KHTILADIVI SAAGIPNLIT ADMIKEGAAV IDVGINRVHD PVTAKPKLVG DVDFEGVRQK AGYITPVPGG VGPMTVAMLM KNTIIAAKKV LRLEEREVLK SKELGVATN
靶标信息
This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; NAD-dependent methylene tetrahydrofolate dehydrogenase cyclohydrolase
基因别名: MTHFD2; NMDMC
UniProt ID: (Human) P13995
Entrez Gene ID: (Human) 10797
