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产品信息
MA5-15844
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
已发表种属
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
5D3
抗原
Purified recombinant fragment of human MTHFR expressed in E. Coli.
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存液
ascites
内含物
0.03% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11154428
产品详细信息
MA5-15844 targets MTHFR in indirect ELISA, IHC and WB applications and shows reactivity with Human and Rat samples.^M
^M
The MA5-15844 immunogen is purified recombinant fragment of human MTHFR expressed in E. Coli. .^M
^M
MA5-15844 detects MTHFR which has a predicted molecular weight of approximately 75kDa.
靶标信息
The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 5,10-methylenetetrahydrofolate reductase (NADPH); methylenetetrahydrofolate reductase; Methylenetetrahydrofolate reductase (NADPH); RP11-56N19.4
基因别名: MTHFR
UniProt ID: (Human) P42898
Entrez Gene ID: (Human) 4524, (Rat) 362657
response to hypoxia
cellular amino acid metabolic process
methionine metabolic process
blood circulation
regulation of histone methylation
response to vitamin B2
tetrahydrofolate interconversion
response to drug
response to amino acid
S-adenosylmethionine metabolic process
folic acid metabolic process
homocysteine metabolic process
response to folic acid
oxidation-reduction process
response to interleukin-1
heterochromatin maintenance
one-carbon metabolic process
methionine biosynthetic process
tetrahydrofolate metabolic process
