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产品信息
MA5-13871
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
已发表种属
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
1032
抗原
Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells
偶联物
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 0.05% BSA
内含物
0.05% sodium azide
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_10989340
产品详细信息
MA5-13871 targets Major Vault Protein in FACS, GS, IHC (P), IP, and WB applications and shows reactivity with Human and Rat samples.
The MA5-13871 immunogen is proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells.
靶标信息
This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Lung resistance-related protein; Major vault protein; MVP; MVP1; Testicular Secretory Protein Li 30; VAULT1; vRNP
基因别名: LRP; MVP; VAULT1
UniProt ID: (Human) Q14764, (Rat) Q62667
Entrez Gene ID: (Human) 9961, (Rat) 64681
