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产品信息
PA5-37180
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to residues in human Myosin-8
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2553944
产品详细信息
This antibody detects endogenous protein at a molecular weight of 223 kDa.
Purity is >95% by SDS-PAGE.
靶标信息
Myosin is a highly conserved, ubiquitously expressed protein that interacts with Actin to generate the force for cellular movements. Conventional Myosins are hexameric proteins consisting of two heavy chain subunits, a pair of non-phosphorylatable light chain subunits and a pair of phosphorylatable light chain subunits. Three general classes of Myosin have been cloned: smooth muscle Myosins, striated muscle Myosins and non-muscle Myosins. Contractile activity in smooth muscle is regulated by the calcium/calmodulin-dependent phosphorylation of Myosin light chain (MLC) by Myosin light chain kinase. Myosin heavy chains, which are encoded by the MYH gene family, contain Actin-activated ATPase activity which generates the motor function of Myosin. Myosin heavy chains were initially isolated from a human fetal skeletal muscle and are the major determinant in the speed of contraction of skeletal muscle. Various isoforms of myosin heavy chains are differentially expressed depending on the functional activity of the muscle.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Beta-MHC antisense; fetal-myosin heavy chain; MyHC-perinatal; Myosin 8; Myosin heavy chain 8; Myosin heavy chain, skeletal muscle, perinatal; myosin, heavy chain 8, skeletal muscle, perinatal; myosin, heavy polypeptide 8, skeletal muscle, perinatal; Myosin-8; Myosin8
基因别名: 4832426G23Rik; AI327267; DA7; gtMHC-F; MHCp; MYH8; MyHC-peri; MyHC-pn; Myhs-p; Myhsp
UniProt ID: (Human) P13535, (Mouse) P13542
Entrez Gene ID: (Human) 4626, (Rat) 252942, (Mouse) 17885
