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Metallothionein Antibody (MA5-27587) in WB
Western blot analysis of Metallothionein in pseudomonas aeruginosa metallothionein (pmta) gst tagged using 1 µg of protein. Sample was prepared with 5% milk and TBST, incubated with Metallothionein monoclonal antibody (Product # MA5-27587) using a dilution of 1:1000 (2 hours at RT) and followed by a Goat Anti-Mouse HRP secondary antibody at a dilution of 1:5000 (1 hour at RT). Samples are arranged as follows: Lane 1: molecular weight ladder, Lane 2: GST, Lane 3: Purified Pseudomonas aeruginosa Metallothionein (PmtA) GST tagged.
产品信息
MA5-27587
产品规格
种属反应
Bacteria
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
8D8
抗原
Full length Pseudomonas aeruginosa Metallothionein protein
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2735269
产品详细信息
A 1:1,000 dilution of MA5-27587 was sufficient for detection of Metallothionein in 1 µg of purified Pseudomonas aeruginosa Metallothionein (PmtA)-GST tagged protein by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.|Detects 36 kDa band corresponding to Pseudomonas aeruginosa Metallothionein.
靶标信息
This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions. The conserved cysteine residues co-ordinate metal ions using mercaptide linkages. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. Disruption of two metallothionein genes in mouse resulted in defects in protection against heavy metals, oxidative stress, immune reactions, carcinogens, and displayed obesity. MT1A (Metallothionein 1A) is a Protein Coding gene. Diseases associated with MT1A include Menkes Disease and Deficiency Anemia. Among its related pathways are Metal ion SLC transporters and Cellular responses to stimuli. An important paralog of this gene is MT2A.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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