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产品信息
PA5-24145
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 160-189 amino acids from the C-terminal region of human BHLHA15
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2541645
靶标信息
Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: basic helix-loop-helix domain containing, class B, 8; basic helix-loop-helix family, member a15; bHLHa15; bHLHb8; Class A basic helix-loop-helix protein 15; Class B basic helix-loop-helix protein 8; class II bHLH protein MIST1; MIST-1; Muscle, intestine and stomach expression 1
基因别名: 1810009C13Rik; BHLHA15; BHLHB8; MIST-1; MIST1
UniProt ID: (Human) Q7RTS1, (Mouse) Q9QYC3
Entrez Gene ID: (Human) 168620, (Mouse) 17341
transcription from RNA polymerase II promoter
mitochondrial calcium ion transport
Golgi organization
G-protein coupled receptor signaling pathway
cell-cell signaling
negative regulation of myotube differentiation
calcium-mediated signaling
endoplasmic reticulum unfolded protein response
cellular response to glucose starvation
glucose homeostasis
positive regulation of transcription from RNA polymerase II promoter
intracellular distribution of mitochondria
cell maturation
transcription, DNA-templated
regulation of transcription, DNA-templated
