Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 1
Mitofilin Antibody (PA5-89627) in WB
Western blot analysis of Mitofilin in extracts of various cell lines. Samples were incubated with Mitofilin Polyclonal antibody (Product # PA5-89627) using a dilution of 1:400, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
PA5-89627
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human IMMT (NP_0068302)
偶联物
形式
Liquid
浓度
0.64 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805695
产品详细信息
Positive Samples: SW480, SW620, H460, HepG2, Mouse spleen, Mouse testis; Cellular Location: Mitochondrion, Mitochondrion inner membrane, Single-pass membrane protein
Immunogen sequence: EELEKMKSVI ENAKKKEVAG AKPHITAAEG KLHNMIVDLD NVVKKVQAAQ SEAKVVSQYH ELVVQARDDF KRELDSITPE VLPGWKGMSV SDLADKLSTD D
靶标信息
Mitofilin is a transmembrane protein of the inner mitochondrial membrane and it is associated with a large multimeric protein complex of about 1200 kDa. Mitofilin has critical functions in mitochondrial morphology and mitochondrial fusion and fission, specifically in the formation of tubular cristae and cristae junctions. Abnormal mitochondrial morphology has been implicated in many human diseases such as myopathy, cardiomyopathy, rhabdomyosarcoma and Whartin's tumor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Cell proliferation-inducing gene 4/52 protein; cell proliferation-inducing protein 52; IMMT antibody; immt {ECO:0000312|EMBL:AAI05842.1, ECO:0000312|RGD:1310684}; MICOS complex subunit MIC60; mitochondrial inner membrane organizing system 2; Mitochondrial inner membrane protein; mitochondrial inner membrane protein {ECO:0000250|UniProtKB:Q8CAQ8, ECO:0000312|EMBL:AAI05842.1}; Mitofilin; mitofilin {ECO:0000250|UniProtKB:Q8CAQ8}; motor protein; p87/89; p87/89 antibody; proliferation-inducing gene 4
基因别名: 1700082C19Rik; D830041H16Rik; HMP; IMMT; MIC60; MINOS2; P87; P87/89; P89; PIG4; PIG52
UniProt ID: (Human) Q16891, (Rat) Q3KR86, (Mouse) Q8CAQ8
Entrez Gene ID: (Human) 10989, (Rat) 312444, (Mouse) 76614
