Invitrogen

Munc13-4 Polyclonal Antibody

Munc13-4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Munc13-4 Antibody (PA5-18550) in IHC (P)

Immunohistochemical analysis of Munc13 4 in paraffin embedded human thymus using a Munc13 4 polyclonal antibody (Product #PA5-18550) at a concentration of 2.5 µg/mL. Steamed antigen retrieval was performed with pH 6 buffered citrate. Samples were then stained with alkaline phosphatase.

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产品信息

PA5-18550

应用

建议稀释比

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免疫印迹 (WB)

1-3 µg/mL

免疫组化（石蜡） (IHC (P))

1-2 µg/mL

产品规格

种属反应

Human, Mouse

宿主/亚型

Goat / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide sequence (ETQKHKKDLHPLFD) corresponding to the internal amino acids of UNC13D (aa 967-980).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Ammonium sulfate precipitation

保存液

TBS, pH 7.3, with 0.5% BSA

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_10981103

产品详细信息

This antibody is predicted to react with bovine, canine, porcine and rat based on sequence homology.

This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.

靶标信息

This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.

仅用于科研。不用于诊断过程。未经明确授权不得转售。