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Invitrogen
Myeloperoxidase Monoclonal Antibody (2C7)
高级验证
This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.
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Myeloperoxidase Antibody (MA1-34067) in ICC/IF
Immunofluorescence analysis of MPO was performed using HL-60 cells treated with 1 micromolar Retinoic Acid for 96Hrs. The cells were fixed with 4% Paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 2% BSA for 10 minutes at room temperature. The cells were labeled with Myeloperoxidase Monoclonal Antibody (2C7) (Product # MA1-34067) at 1:100 dilution in 0.1... View More
产品信息
MA1-34067
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
2C7
抗原
Human myeloperoxidase
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_1956783
产品详细信息
A suggested positive control for this product is bone marrow.
靶标信息
Myeloperoxidase (MPO) is a heme protein that is synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single chain precursor and subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme is responsible for producing hypohalous acids that are central to the microbicidal activity of neutrophils. Diseases that are associated with MPO include Myeloperoxidase Deficiency and Alzheimer's Disease, Familial, 1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
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hypochlorous acid biosynthetic process
respiratory burst involved in defense response
defense response
response to oxidative stress
aging
response to mechanical stimulus
removal of superoxide radicals
response to food
response to lipopolysaccharide
low-density lipoprotein particle remodeling
hydrogen peroxide catabolic process
negative regulation of apoptotic process
negative regulation of growth of symbiont in host
defense response to fungus
oxidation-reduction process
response to gold nanoparticle
