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产品信息
PA5-114224
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the C-terminal region of Mouse Mstn
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2884738
产品详细信息
Immunogen sequence: APKRYKANYC SGECEFVFLQ KYPHTHLVHQ ANPRGSAGPC CTPTKMSPIN
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%;
靶标信息
The protein encoded by this gene is a member of the bone morphogenetic protein family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: compact; GDF-8; growth differentiation factor 8; Growth/differentiation factor 8; H-Myo-Propeptide; H-Myostatin; Myostatin
基因别名: Cmpt; Gdf8; Mstn
UniProt ID: (Mouse) O08689
Entrez Gene ID: (Mouse) 17700
positive regulation of defense response to virus by host
transforming growth factor beta receptor signaling pathway
positive regulation of pathway-restricted SMAD protein phosphorylation
negative regulation of muscle hypertrophy
growth
regulation of apoptotic process
regulation of MAPK cascade
negative regulation of myoblast differentiation
positive regulation of transcription, DNA-templated
muscle cell cellular homeostasis
cell development
negative regulation of skeletal muscle tissue growth
negative regulation of protein kinase B signaling
SMAD protein signal transduction
cellular response to dexamethasone stimulus
mitophagy in response to mitochondrial depolarization
