Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
MA5-31804
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
6E4B2
抗原
Purified recombinant fragment of human MSTN (AA:24-266) expressed in E. coli.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2787427
产品详细信息
MA5-31804 has been tested in indirect ELISA.
靶标信息
The protein encoded by this gene is a member of the bone morphogenetic protein family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: GDF-8; Growth/differentiation factor 8; H-Myo-Propeptide; H-Myostatin; Myostatin
基因别名: GDF8; MSLHP; MSTN
UniProt ID: (Human) O14793
Entrez Gene ID: (Human) 2660
positive regulation of defense response to virus by host
transforming growth factor beta receptor signaling pathway
muscle organ development
response to heat
response to gravity
positive regulation of pathway-restricted SMAD protein phosphorylation
skeletal muscle atrophy
negative regulation of muscle hypertrophy
response to muscle activity
ovulation cycle process
response to testosterone
negative regulation of kinase activity
regulation of apoptotic process
skeletal muscle tissue regeneration
regulation of MAPK cascade
response to estrogen
response to ethanol
negative regulation of myoblast differentiation
positive regulation of transcription, DNA-templated
negative regulation of insulin receptor signaling pathway
muscle cell cellular homeostasis
cell development
negative regulation of skeletal muscle tissue growth
response to electrical stimulus
negative regulation of protein kinase B signaling
SMAD protein signal transduction
cellular response to dexamethasone stimulus
mitophagy in response to mitochondrial depolarization
xenophagy
negative regulation of skeletal muscle satellite cell proliferation
negative regulation of satellite cell differentiation
negative regulation of myoblast proliferation
