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Sequence of this protein is as follows: MALGYWRAGR ARDAAEFELF FRRCPFGGAF ALAAGLRDCV RFLRAFRLRD ADVQFLASVL PPDTDPAFFE HLRALDCSEV TVRALPEGSL AFPGVPLLQV SGPLLVVQLL ETPLLCLVSY ASLVATNAAR LRLIAGPEKR LLEMGLRRAQ GPDGGLTAST YSYLGGFDSS SNVLAGQLRG VPVAGTLAHS FVTSFSGSEV PPDPMLAPAA GEGPGVDLAA KAQVWLEQVC AHLGLGVQEP HPGERAAFVA YALAFPRAFQ GLLDTYSVWR SGLPNFLAVA LALGELGYRA VGVRLDSGDL LQQAQEIRKV FRAAAAQFQV PWLESVLIVV SNNIDEEALA RLAQEGSEVN VIGIGTSVVT CPQQPSLGGV YKLVAVGGQP RMKLTEDPEK QTLPGSKAAF RLLGSDGSPL MDMLQLAEEP VPQAGQELRV WPPGAQEPCT VRPAQVEPLL RLCLQQGQVA APPPSS
Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FHA-HIT-interacting protein; NAPRTase; Nicotinate phosphoribosyltransferase; nicotinate phosphoribosyltransferase domain containing 1; Nicotinate phosphoribosyltransferase domain-containing protein 1; nicotinic acid phosphoribosyltransferase
基因别名: FHIP; NAPRT; NAPRT1; PP3856
UniProt ID: (Human) Q6XQN6
Entrez Gene ID: (Human) 93100
分子生物学功能:
glycosyltransferase
transferase
metabolite interconversion enzyme