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NBPF6 Antibody (PA5-103962) in ICC/IF
Immunocytochemistry analysis of NBPF6 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with NBPF6 polyclonal antibody (Product # PA5-103962) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
产品信息
PA5-103962
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human NBPF6(Accession Q5VWK0), corresponding to amino acid residues E505-L555.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2853294
产品详细信息
Antibody detects endogenous levels of total NBPF6.
靶标信息
Members of the neuroblastoma breakpoint family are encoded by genes that map to a region of segmental duplications on human chromosome 1. Both NBPF4 (neuroblastoma breakpoint family member 4) and NBPF6 (neuroblastoma breakpoint family member 6) are cytoplasmic proteins that belong to the NBPF family. NBPF4 contains 123 amino acids and is expressed in testis, while NBPF6 consists of 638 amino acids and contains 3 NBPF domains. Like other NBPF family members, both proteins are encoded by genes that map to human chromosome 1p13.3. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome.
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生物信息学
蛋白别名: Neuroblastoma breakpoint family member 6; neuroblastoma breakpoint family, member 6
基因别名: NBPF6
UniProt ID: (Human) Q5VWK0
Entrez Gene ID: (Human) 653149
