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Immunogen sequence: RKNSARKASI VKNLKDTLGI GKVKRKPSVP DSASPADDSF VDPGERLYDL NMPAYVKFNY MAEREDELSL IKGTKVIVME KCSDGWWRGS YNGQVGWFPS NYVTEEGDSP LGDHVGSLSE KLAAVVNNLN TGQVLHVVQA LYPFSSSNDE ELNFEKGDVM DVIEKPENDP EWWKCRKING MVGLVPKNYV TVMQNNPLTS GLEPSPPQCD YIRPSLTGKF AGNPWYYGKV TRHQAEMALN ERGHEGDFLI RDSESSPNDF SVSLKAQGKN KHFKVQLKET VYCIGQRKFS TMEELVEHYK KAPIFTSEQG EKLYLVKHLS; Positive Samples: Mouse brain; Cellular Location: Cytoplasm, Endoplasmic reticulum, Nucleus
NCK1 is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cytoplasmic protein Nck1; MGC12668; NCK adapter protein 1; NCK adaptor protein 1; Nck-1; SH2/SH3 adapter protein Nck1
基因别名: 6330586M15Rik; D230010O13Rik; Nck; Nck-1; Nck1
UniProt ID: (Mouse) Q99M51
Entrez Gene ID: (Mouse) 17973
分子生物学功能:
scaffold/adaptor protein