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产品信息
H00057447-M10
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
1D6
抗原
NDRG2 (AAH11240, 1 a.a. approximately 360 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MAELQEVQIT EEKPLLPGQT PEAAKEAELA ARILLDQGQT HSVETPYVSV TFTVYGTPKP KRPAILTYHD VGLNYKSCFQ PLFQFEDMQE IIQNFVRVHV DAPGMEEGAP VFPLGYQYPS LDQLADMIPC VLQYLNFSTI IGVGVGAGAY ILARYALNHP DTVEGLVLIN IDPNAKGWMD WAAHKLTGLT SSIPEMILGH LFSQEELSGN SELIQKYRNI ITHAPNLDNI ELYWNSYNNR RDLNFERGGD ITLRCPVMLV VECNSKLDPT QTSFLKMADS GGQPQLTQPG KLTEAFKYFL QGMGYMASSC MTRLSRSRTA SLTSAASVDG NRSRSRTLSQ SSESGTLSSG PPGHTMEVSC
靶标信息
NDRG2's gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. NDRG2 is a cytoplasmic protein that may play a role in neurite outgrowth. Its gene may be involved in glioblastoma carcinogenesis.This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cytoplasmic protein Ndr1; DKFZp781G1938; FLJ25522; N-myc downstream regulator 2; N-myc downstream-regulated gene 2 protein; NDR1-related protein NDR2; NDRG2var; Protein NDRG2; Protein Syld709613; syld709613 protein
基因别名: KIAA1248; NDRG2; SYLD
UniProt ID: (Human) B3KUE3
Entrez Gene ID: (Human) 57447
negative regulation of cytokine production
signal transduction
regulation of vascular endothelial growth factor production
Wnt signaling pathway
substantia nigra development
cell differentiation
negative regulation of smooth muscle cell proliferation
negative regulation of ERK1 and ERK2 cascade
regulation of platelet-derived growth factor production
