Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-50614
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region derived from internal residues of human NIMA-related kinase 1
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2636067
产品详细信息
The antibody detects endogenous levels of total NEK1 protein.
靶标信息
NEK1 is a serine/threonine protein kinase, related to the NIMA cell cycle regulator, and is highly expressed in meiotic germ cells. The kinase may function early in the DNA damage response pathway. NEK1 may also participate in polycystic kidney disease and neural cell development. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: DKFZp686D06121; DKFZp686K12169; kidney, anemia and testis; MGC138800; Nek1 serine/threonine- and tyrosine-specific protein kinase; Never in mitosis A-related kinase 1; NIMA (never in mitosis gene a)-related kinase 1; NIMA-related kinase 1; NimA-related protein kinase 1; NY REN55; NY-REN-55 antigen; protein-serine/threonine kinase; Renal carcinoma antigen NY-REN-55; Serine/threonine-protein kinase Nek1
基因别名: D8Ertd790e; kat; KIAA1901; NEK1; NY-REN-55; SRPS2; SRPS2A; SRTD6
UniProt ID: (Human) Q96PY6, (Mouse) P51954
Entrez Gene ID: (Human) 4750, (Mouse) 18004
protein kinase activity
receptor signaling protein serine/threonine kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
kinase activity
metal ion binding
nucleotide binding
protein serine/threonine kinase activity
MAP kinase kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
protein phosphorylation
mitotic nuclear division
peptidyl-tyrosine phosphorylation
signal transduction by protein phosphorylation
cilium assembly
cell division
MAPK cascade
activation of MAPK activity
kidney development
cellular response to DNA damage stimulus
cell cycle
spermatogenesis
response to ionizing radiation
phosphorylation
cell projection organization
multicellular organism growth
