Target of Interest
Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Application
图: 1 / 5
NEUROD4 Antibody (PA5-115642) in ICC/IF
Immunocytochemistry analysis of NEUROD4 in A549 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115642). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
产品信息
PA5-115642
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human NEUROD4(Accession Q9HD90), corresponding to amino acid residues Y41-K91.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2900277
产品详细信息
Antibody detects endogenous levels of total NEUROD4.
靶标信息
Probably acts as a transcriptional activator. Mediates neuronal differentiation. Required for the regulation of amacrine cell fate specification in the retina.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: ATH-3; atonal homolog 3; bHLHa4; Class A basic helix-loop-helix protein 4; Helix-loop-helix protein mATH-3; mATH3; NeuroD4; neurogenic differentiation 4; Neurogenic differentiation factor 4; Protein atonal homolog 3
基因别名: AI846749; ATH-3; ATH3; ATOH3; BHLHA4; MATH-3; MATH3; NEUROD4
UniProt ID: (Human) Q9HD90, (Mouse) O09105
Entrez Gene ID: (Human) 58158, (Mouse) 11923, (Rat) 288821
neuron migration
transcription, DNA-templated
regulation of transcription, DNA-templated
Notch signaling pathway
neuroblast proliferation
glial cell differentiation
amacrine cell differentiation
cell fate commitment
positive regulation of cell differentiation
neuron development
multicellular organism development
nervous system development
cell differentiation
camera-type eye development
retina development in camera-type eye
