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Immunogen sequence: SADEEEEEEP GASGGARRQR GAEAGQGARG GVAAGAEGCR PARLLGLVHD CKRRPSRARA VSRGAKTAET VQRIKKT
Neurogenin-2 is a member of the neurogenin subfamily of basic helix-loop-helix (bHLH) transcription factor genes that play an important role in neurogenesis from migratory neural crest cells. In the course of mouse neurogenesis, Ngn2 and Ngn1 are expressed in distinct progenitor populations residing in the central and peripheral nervous systems. Mutation analyses demonstrate that Ngn1 is required for the determination of neuronal precursors for proximal cranial sensory ganglia and that Ngn2 is necessary for the determination of precursors for epibranchial placode-derived sensory neurons.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: bHLHa8; Class A basic helix-loop-helix protein 8; Neurogenin-2; neurogenin2; NGN-2; Protein atonal homolog 4
基因别名: ATOH4; BHLHA8; Math4A; NEUROG2; ngn-2; NGN2
UniProt ID: (Human) Q9H2A3
Entrez Gene ID: (Human) 63973