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产品信息
PA5-52317
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2644693
产品详细信息
Immunogen sequence: FLSLLCPGLR IPQLSVLCAQ PRPRAMAISS SSCELPLVAV CQVTSTPDKQ QNFKTCAELV REAARLGACL AFLPEAFDFI ARDPAETLHL SEPLGGKLLE EYTQLARECG LWLSLGGFHE RGQDWEQT
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 67%.
靶标信息
Plays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Deaminated glutathione amidase; dGSH amidase; MGC57670; Nitrilase homolog 1
基因别名: NIT1
UniProt ID: (Human) Q86X76
Entrez Gene ID: (Human) 4817
